About Orthologene

Orthologene is a resource for gene orthology. We want to unearth the evolutionary history of every human gene, and present this history in a simple way that still allows powerful exploration, and understanding of gene functions in any organism.

Orthologene is a project of the Manning Lab at the Salk Institute, and grows out of our work focused on the evolution of protein kinases. We learned a lot from manually exploring the origins of kinases, and are now working hard to apply the same principles to the entire genome.

For now, Orthologene will provide broad information on homology, orthology and paralogy, and links to public resources and databases. We hope soon to add our own data and visualization tools. Stay tuned!